‘Doctor Odyssey’: New Trailer Reveals John Stamos, Gina Gershon & More Guest Stars

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We’re just days away from the embarkation of ABC‘s series premiere of Doctor Odyssey. This intriguing new medical drama takes place onboard a fancy cruise ship with some “big deck energy.”

While we still have some big questions about what’s ahead in the new Ryan Murphy show (particularly, is everything actually as it seems here or is there a major twist?), a lot of intriguing details have been revealed … including a list of some very major guest stars. Read on to find out everything we know for sure so far about Doctor Odyssey.

When does Doctor Odyssey premiere?

The medical drama will debut on Thursday, September 26 at 9/8c, following 9-1-1 Season 8‘s premiere and leading into Grey’s Anatomy Season 21‘s premiere.

Is there a Doctor Odyssey trailer?

Yes! Embedded above, the newest trailer for the series reveals a slew of major guest stars ahoy, including Shania Twain, John Stamos, Gina Gershon, Kelsea Ballerini, Chord Overstreet, Cheyenne Jackson, Laura Harrier, Stephanie Suganami, and Justin Jedlica. Plus, it’s clear there’s going to be some steamy hookups, major medical saves, and amazing landscapes.

ABC previously released a teaser for Doctor Odyssey on social media (embedded below). In it, Don Johnson’s character tells a tuxedo-clad Max, “This ship is heaven” but warns, “Doctor, it’s your job to keep everybody alive.” We then get a taste of the drama ahead as a soaked Max tries to rescue someone with paddles on a lifeboat.

ABC has released the first official promo for Ryan Murphy’s “Doctor Odyssey!” ️ pic.twitter.com/olFqgrJ6Ob— The AHS Zone (@AHSZone) August 1, 2024

Who stars in Doctor Odyssey?

The cast is led by Joshua Jackson as Max, a charming new on-board doctor for a luxury cruise ship whose team navigates various medical crises on the high seas — and has fun when the emergencies aren’t happening. Don Johnson and Philippa Soo also star in the series.

Also joining the cast is country music superstar Shania Twain, who appears as a potential love interest for Johnson’s character.

What is Doctor Odyssey about?

ABC’s official logline for the show is as follows: “Max is the new on-board doctor for a luxury cruise ship where the staff works hard and plays harder. It’s all hands on deck as Max and his small but mighty medical team navigate unique medical crises and each other, miles from shore.” In other words, it’s essentially Royal Pains meets The Love Boat.

ABC/Disney

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